Assassin's Creed III is a 2012 action-adventure video game developed by Ubisoft Montreal and published by Ubisoft for PlayStation 3, Xbox 360, Wii U, and Microsoft Windows. It is the fifth major installment in the Assassin's Creed series, and a direct sequel to 2011's Assassin's Creed: Revelations. The game was released worldwide for PlayStation 3 and Xbox 360, beginning in North America on October 30, 2012, with a Wii U and Microsoft Windows release following in November 2012.

The plot is set in a fictional history of real world events and follows the centuries old struggle between the Assassins, who fight for free will, and the Templars, who desire control over mankind. The framing story is set in the 21st century and features series protagonist Desmond Miles who, with the aid of a machine known as the Animus, relives the memories of his ancestors to find a way to avert the 2012 apocalypse. The story proper is set in the 18th century, before, during and after the American Revolution from 1753 to 1783, and follows Desmond's half-English, half-Mohawk ancestor, Ratonhnhak�:ton (pron.: /ˈrəduːnˈhəɡeɪduːn/; "Ra-doon-ha-gay-doon"), also known as Connor, as he fights the Templars' attempts to gain control of the newly forming nation.

Assassin's Creed III is set in an open world and presented from the third-person perspective with a primary focus on using Desmond and Connor's combat and stealth abilities to eliminate targets and explore the environment. Connor is able to freely explore 18th-century Boston, New York and the American frontier to complete side missions away from the primary storyline. The game also features a multiplayer component, allowing players to compete online to complete solo and team based objectives including assassinations and evading pursuers. Ubisoft developed a new game engine, Anvil Next, for the game. The game was met with positive reviews and has sold 12 million copies worldwide.

A prequel to the game titled Assassin's Creed IV: Black Flag was announced in early 2013, and is set to follow Connor's grandfather as a pirate in the Caribbean.